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PhD Position (f/m/d)

Organizational unit

Institute for Advanced Membrane Technology (IAMT)

Job description

This PhD project aims to develop and apply a biocatalytic membrane for degradation of steroid hormone micropollutants. The project will focus on i) selection of different enzymes based on the enzymatic degradation process that occurs in human body, ii) explore different methods for the enzyme immobilization on the membrane by using green solvents and biocompatible materials, ii) investigate the enzymatic degradation process in small scale filtration system to evaluate the efficiency of hormone removal.

The three main research questions of the project are:

  • What are the existent enzymatic degradation mechanisms of steroid hormones in nature and how can be reproduced in a membrane filtration support?
  • What is the most suitable immobilization method on the membrane able to keep high specific activity and enzyme loading?
  • What is the role of solute-membrane partitioning and system mass transfer in the control of the enzymatic degradation during filtration?

The PhD project will be largely experimental and will begin with an identification of a set of research questions based on detailed literature survey. The preliminary research proposal required for application (with a timetable for the 3 to 4 year research project) will be further expanded to 4 main experimental chapters. Required equipment will be set up and further development of relevant analytical methods will follow. Execution of the research plan through conducting of experiments, sample and data analysis and write up of results for scientific publication are part of the PhD process – a journey to become an independent researcher! Throughout the project, there will be multiple opportunities for cooperation with internal and external partners, supervising bachelor and master students, giving oral presentations at conferences, writing high-impact journal articles, as well as sharing your knowledge via teaching.

Starting date

01.09.2021

Personal qualification

You will most likely already hold a Masters in Chemical, Process, Bio-Engineering, or equivalent. You are a naturally curious person who is eager to learn more and has a strong interest in research. Experience with membrane filtration systems (of any scale) is a definite advantage, as well as being comfortable in specifying system components and sound experimental problem solving skills – as well a good common sense. Excellent English language proficiency is essential, basic German language skills of advantage.

Contract duration

1 year

Application up to

15.06.2021

Contact person in line-management

For further information, please contact Dr. Alessandra Imbrogno Tel. +49 (0)721 60824361, alessandra.imbrogno@kit.edu, https://www.iamt.kit.edu

Canditature

Please send your application including CV, publication list and your contribution to the publication (if relevant), academic transcripts, degree certificates, contact details for three references and a preliminary research proposal in electronic form to:

alessandra.imbrogno@kit.edu

We prefer to balance the number of female and male employees. Therefore, we kindly encourage female applicants to apply for this job.

Recognized severely disabled persons will be preferred if they are equally qualified.