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IMT 27-21 Internship: Toxicity evaluation with Escherichia coli

Organizational unit

Institute of Microstructure Technology (IMT)

Job description

Nuclear magnetic resonance is an analysis tool with several advantages, such as being non-invasive and allowing real-time monitoring. Thus, it offers great opportunities for cell and cell metabolism monitoring over extended periods. However, one of the disadvantages is the low sensitivity of NMR. To overcome this disadvantage there are different hyperpolarization techniques which enhance the NMR signals. For the application of those technologies, bacteria need to be exposed to an NMR signal amplification chemical. Hence, the biocompatibility of this chemical needs to be examined through toxicity evaluation with a custom E. coli strain.


  • Cell handling and culturing
  • Generating of toxicity experiment design
  • Concentration determination and diluting experiments
  • Evaluating toxicity test results

This internship offers the opportunity of learning cell handling and culturing as well as working in an S1 bio lab. Additionally, first experience can be collected in planning and preparing experiments and gaining first insight into the work in research.

Starting date

by appointment

Personal qualification

  • studies in Biological engineering, mechanical engineering, chemical engineering or similiar
  • First experience with work in a S1 biology lab and cell handling are of advantage
  • self-motivated and independent working
  • good English skills are of advantage

Contract duration

upon consultation

Contact person in line-management

For further information, please contact M.Sc. Julia Schulte Hermann, phone: +49 721 608-29311, email:

Please apply online using the button below for this vacancy number IMT 27-21.

Ausschreibungsnummer: IMT 27-21

Recognized severely disabled persons will be preferred if they are equally qualified.


Personnel Support is provided by:
Personalservice (PSE) - Human Resources
Ms Carrasco Sanchez
Phone: +49 721 608-42016,

Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany